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The human body typically begins to be colonized by its normal biota


A) before birth,in utero.
B) during and immediately after birth.
C) when a child first goes to school.
D) when an infant gets its first infectious disease.
E) during puberty.

F) B) and D)
G) C) and D)

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A

A fetus can get an infection when a pathogen in the mother's blood is capable of crossing the placenta to the fetal circulation and tissues.

A) True
B) False

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Virulence factors include all the following except ________.


A) capsules
B) ribosomes
C) exoenzymes
D) endotoxins
E) exotoxins

F) C) and D)
G) B) and D)

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B

The effect of "good" microbes against invading microbes is called ________.


A) microbial antagonism
B) endogenous infection
C) infectious disease
D) axenic
E) gnotobiotism

F) A) and B)
G) B) and E)

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________ are toxins that are the lipopolysaccharide of the outer membrane of gram-negative cell walls.


A) Exotoxins
B) Endotoxins
C) Enterotoxins
D) Leukocidins
E) Hemolysins

F) C) and D)
G) A) and B)

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B

All infectious diseases ________.


A) are contagious
B) occur only in humans
C) are caused by microorganisms or their products
D) are caused by vectors
E) involve viruses as the pathogen

F) C) and E)
G) B) and E)

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A ________ is an infection indigenous to animals that can,on occasion,be transmitted to humans.


A) secondary infection
B) sequelae
C) nosocomial infection
D) zoonosis
E) None of the choices are correct.

F) B) and C)
G) A) and B)

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A 78-year-old male presents to the emergency department reporting a 2-day history of difficulty breathing, cough, and chest pain. Upon triage assessment, the patient is found to have a fever, rapid rate of breathing, low oxygen saturation, and crackles upon auscultation of the lungs. A chest X-ray reveals consolidation in the right upper lung field. The patient is diagnosed with pneumonia, initiated on oxygen therapy, and admitted for observation and treatment. -As the RN,you document the care and assessment of the patient in the chart prior to transfer to an inpatient unit.What is the most appropriate term for the clinical manifestations of disease as noted in your assessment?  


A) Signs
B) Symptoms
C) Syndromes
D) Signs and symptoms

E) A) and B)
F) A) and C)

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A 78-year-old male presents to the emergency department reporting a 2-day history of difficulty breathing, cough, and chest pain. Upon triage assessment, the patient is found to have a fever, rapid rate of breathing, low oxygen saturation, and crackles upon auscultation of the lungs. A chest X-ray reveals consolidation in the right upper lung field. The patient is diagnosed with pneumonia, initiated on oxygen therapy, and admitted for observation and treatment. -The patient's sputum culture returns a positive result for Streptococcus pneumoniae.As the RN,you are aware this capsule-forming bacterium possesses virulence factors to make it difficult to treat.In providing education to the patient regarding the disease process,which of the following statements is most appropriate?  


A) "Fluid is building up in your lungs because of the body's persistent inflammatory response to the microbe."
B) "This bacterium secretes toxins that directly damage your lungs."
C) "Fragments of this bacterium's cell wall directly harm your lungs."
D) "Fluid is building up in your lungs because white blood cells are effectively lysing the encapsulated bacteria."

E) All of the above
F) A) and D)

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An animal,such as an arthropod,that transmits a pathogen from one host to another is a ________.


A) fomite
B) carrier
C) vector
D) reservoir
E) source

F) None of the above
G) D) and E)

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What is one goal of the Human Microbiota Project?


A) To sequence the DNA of all microorganisms
B) To study the prevalence of disease
C) To study microorganisms in their natural habitat
D) To provide comprehensive characterization of microbiota relating to human health and disease
E) To discover new organisms in extreme habitats

F) C) and D)
G) A) and C)

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When an infected person is in the incubation period,that person cannot transmit the pathogen to others.

A) True
B) False

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A 36-year-old female is bit by a raccoon and presents to the emergency department with mild trauma to her right lower extremity. Following a triage assessment, the patient's wound is cleaned and dressed. The physician verbalizes concern that the patient may have been exposed to rabies from the bite. One role of the RN is to provide education to the patient regarding rabies infection and its transmission. -Which of the following terms most appropriately describes the role of the raccoon in the patient's exposure to infection?  


A) Living reservoir
B) Nonliving reservoir
C) Carrier
D) Biological vector

E) A) and B)
F) B) and C)

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Exotoxins


A) are secreted by pathogenic organisms.
B) are bound to the membrane of pathogenic organisms.
C) are bound to the cell wall of pathogenic organisms.
D) cause more damage than endotoxins.
E) are host specific.

F) A) and E)
G) B) and D)

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A 36-year-old female is bit by a raccoon and presents to the emergency department with mild trauma to her right lower extremity. Following a triage assessment, the patient's wound is cleaned and dressed. The physician verbalizes concern that the patient may have been exposed to rabies from the bite. One role of the RN is to provide education to the patient regarding rabies infection and its transmission. -If the patient develops rabies infection,you know that it must be reported to local and state public health officials.Which of the following diseases is also reportable in the United States?


A) Pinworm infection
B) Fifth disease
C) EBV infection
D) Cholera

E) B) and C)
F) B) and D)

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Which terminology is not used to describe members of the resident biota?


A) Pathogenic biota
B) Normal biota
C) Indigenous biota
D) Normal microbiota
E) Commensals

F) A) and E)
G) B) and D)

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The stage of an infectious disease when specific signs and symptoms are seen and the pathogen is at peak activity is the ________.


A) prodromal stage
B) convalescent stage
C) incubation period
D) period of invasion
E) None of the choices are correct.

F) A) and C)
G) B) and C)

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Microbial hyaluronidase,coagulase,and streptokinase are examples of ________.


A) adhesive factors
B) exotoxins
C) hemolysins
D) antiphagocytic factors
E) exoenzymes

F) B) and D)
G) C) and D)

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Pathogenic microbes that cause disease in healthy people are called ________.


A) opportunistic pathogens
B) normal biota
C) indigenous biota
D) true pathogens
E) micropathogens

F) B) and C)
G) A) and E)

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As an RN with the infectious disease team, you are providing an education course to new graduate nurses regarding the process of infection control and prevention. -As the RN,you educate the new nurses about the prevalence of healthcare-associated infections.All of the following are frequent sources of patient infection,except ________.


A) urinary catheter
B) endotracheal tube
C) surgical incision
D) hospital beds

E) A) and D)
F) A) and B)

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