Question 1

_____ is the most abundant class of antibodies in serum.

Accepted Answer

IgG; Immun...

Question 2

Certain body sites contain sequestered molecules, called _____ that escaped assessment during development of immune tolerance and are mistaken as foreign.

Accepted Answer

The answer of Certain body sites contain sequestered molecules, called...

Question 3

The region of each antibody molecule where amino acid composition is very different from one clone of B lymphocytes to another is the

Accepted Answer

A)   variable region.
B)   joining region.
C)   constant region.
D)   light region.
E)   hinge region.F) All of the above
G) A) and E) A

Question 4

Which process involves antibodies cross-linking cells or particles into large aggregates?

Accepted Answer

A)   neutralization
B)   opsonization
C)   complement fixation
D)   agglutination
E)   anamnestic responseF) C) and E)
G) B) and D)

Question 5

A hybridoma results from the fusion of a myeloma cell with a normal _____ cell.

Accepted Answer

The answer of A hybridoma results from the fusion of...

Question 6

Antigen presenting cells

Accepted Answer

A)   include dendritic cells.
B)   include macrophages.
C)   engulf and modify antigen to be more immunogenic.
D)   hold and present processed antigen on their cell membrane surface.
E)   All of these choices are correct.F) C) and D)
G) B) and C)

Question 7

An example of artificial passive immunity would be

Accepted Answer

A)   chickenpox infection is followed by lifelong immunity.
B)   chickenpox vaccine triggers extended immunity to chickenpox.
C)   giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D)   a fetus acquiring maternal IgG to the chickenpox virus across the placenta.E) B) and C)
F) A) and D) C

Question 8

Properties of effective antigens include all the following, except

Accepted Answer

A)   foreign to the immune system.
B)   molecular complexity.
C)   large molecules with a minimum molecular weight of 1,000.
D)   large polymers made up of identical repeating subunits.
E)   cells or large, complex molecules.F) A) and C)
G) A) and B)

Question 9

Which process involves antibodies covering surface receptors on a virus or toxin molecule thereby disrupting their activity?

Accepted Answer

A)   neutralization
B)   opsonization
C)   complement fixation
D)   agglutination
E)   anamnestic responseF) A) and B)
G) C) and D)

Question 10

Lymphocyte maturation involves

Accepted Answer

A)   hormonal signals that initiate development.
B)   B-cells maturing in bone marrow sites.
C)   T-cells maturing in the thymus.
D)   release of mature lymphocytes to begin migration to various lymphoid organs.
E)   All of these choices are correct.F) C) and D)
G) A) and C)

Question 11

Antibody molecules circulate in lymph, blood, and tissue fluids.

Accepted Answer

A) True 
 B)False

Question 12

Primary and secondary antibody response differ in all the following ways, except

Accepted Answer

A)   IgG production predominates in secondary responses.
B)   the lag period between antigen stimulation and antibody response is shorter in the secondary response.
C)   the rate of antibody production is faster in primary responses than in secondary responses.
D)   primary responses are active whereas secondary responses are passive.E) B) and C)
F) A) and D)

Question 13

Class II MHC genes code for

Accepted Answer

A)   certain secreted complement components.
B)   self receptors recognized by natural killer cells.
C)   all HLA antigens.
D)   receptors located primarily on macrophages, dendritic cells, and B cells.
E)   All of these choices are correct.F) A) and B)
G) C) and E)

Question 14

All of the following are characteristics of an effective vaccine except

Accepted Answer

A)   it should have a relatively long shelf life.
B)   it should stimulate only the antibody B-cell)  response.
C)   it should protect against wild forms of the pathogen.
D)   it should not require numerous boosters.
E)   it should be easy to administer.F) All of the above
G) A) and D)

Question 15

Class I MHC genes code for

Accepted Answer

A)   certain secreted complement components.
B)   markers that display unique characteristics of self.
C)   all HLA antigens.
D)   receptors located primarily on macrophages and B cells.
E)   All of these choices are correct.F) A) and D)
G) B) and C)

Question 16

Which type of cell is severely depressed in AIDS patients?

Accepted Answer

A)   cytotoxic T-cells
B)   helper T-cells
C)   B-cells
D)   pla cells
E)   suppressor T-cellsF) None of the above
G) A) and B)

Question 17

Which is incorrect about the Fc region of an immunoglobulin?

Accepted Answer

A)   It determines the antibody's distribution in the body.
B)   It forms the antigen binding sites.
C)   It contains an effector molecule that can bind to cells such as macrophages and mast cells.
D)   It contains an effector molecule that can fix complement.
E)   It determines the class to which the immunoglobulin belongs.F) None of the above
G) A) and B) B

Question 18

Which cells'direct involvement are required for cell-mediated immunity?

Accepted Answer

A)   T-cells
B)   B-cells
C)   bacterial cells
D)   viral components
E)   neutrophilsF) A) and B)
G) B) and E)

Question 19

Antitoxins

Accepted Answer

A)   contain antibodies to neutralize specific toxin.
B)   use vaccinia virus with genetic material of bacterial toxins.
C)   contain purified, chemically denatured bacterial exotoxin.
D)   include capsule material against the pneumococcus and meningococcus.
E)   contain attenuated organisms.F) C) and D)
G) B) and E)

Question 20

The most significant cells in graft rejection are

Accepted Answer

A)   helper T-cells.
B)   suppressor T-cells.
C)   cytotoxic T-cells.
D)   B-cells.
E)   natural killer NK)  cells.F) A) and B)
G) None of the above

Exam 15: Adaptive, Specific Immunity and Immunization

_____ is the most abundant class of antibodies in serum.

Correct AnswerverifiedIgG; Immun...View AnswerShow Answer

Certain body sites contain sequestered molecules, called _____ that escaped assessment during development of immune tolerance and are mistaken as foreign.

Correct AnswerverifiedShow Answer

The region of each antibody molecule where amino acid composition is very different from one clone of B lymphocytes to another is the

Correct AnswerverifiedA

Which process involves antibodies cross-linking cells or particles into large aggregates?

Correct AnswerverifiedShow Answer

A hybridoma results from the fusion of a myeloma cell with a normal _____ cell.

Correct AnswerverifiedShow Answer

Antigen presenting cells

Correct AnswerverifiedShow Answer

An example of artificial passive immunity would be

Correct AnswerverifiedC

Properties of effective antigens include all the following, except

Correct AnswerverifiedShow Answer

Which process involves antibodies covering surface receptors on a virus or toxin molecule thereby disrupting their activity?

Correct AnswerverifiedShow Answer

Lymphocyte maturation involves

Correct AnswerverifiedShow Answer

Antibody molecules circulate in lymph, blood, and tissue fluids.

Correct AnswerverifiedShow Answer

Primary and secondary antibody response differ in all the following ways, except

Correct AnswerverifiedShow Answer

Class II MHC genes code for

Correct AnswerverifiedShow Answer

All of the following are characteristics of an effective vaccine except

Correct AnswerverifiedShow Answer

Class I MHC genes code for

Correct AnswerverifiedShow Answer

Which type of cell is severely depressed in AIDS patients?

Correct AnswerverifiedShow Answer

Which is incorrect about the Fc region of an immunoglobulin?

Correct AnswerverifiedB

Which cells'direct involvement are required for cell-mediated immunity?

Correct AnswerverifiedShow Answer

Antitoxins

Correct AnswerverifiedShow Answer

The most significant cells in graft rejection are

Correct AnswerverifiedShow Answer

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IgG; Immun...
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C

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B

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